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    Sel1l3 sel-1 suppressor of lin-12-like 3 (C. elegans) [ Mus musculus (house mouse) ]

    Gene ID: 231238, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sel1l3provided by MGI
    Official Full Name
    sel-1 suppressor of lin-12-like 3 (C. elegans)provided by MGI
    Primary source
    MGI:MGI:1916941
    See related
    Ensembl:ENSMUSG00000029189 AllianceGenome:MGI:1916941
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA0746; 2310045A20Rik
    Summary
    Predicted to be located in membrane. Is expressed in several structures, including ganglia; genitourinary system; gut; notochord; and telencephalon. Orthologous to human SEL1L3 (SEL1L family member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 19.0), colon adult (RPKM 18.1) and 18 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Sel1l3 in Genome Data Viewer
    Location:
    5 C1; 5 28.96 cM
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (53264425..53370794, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (53107083..53213452, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 5033403H07 gene Neighboring gene predicted gene, 30301 Neighboring gene STARR-seq mESC enhancer starr_13073 Neighboring gene predicted gene 17182 Neighboring gene solute carrier family 34 (sodium phosphate), member 2 Neighboring gene STARR-seq mESC enhancer starr_13074 Neighboring gene predicted gene, 54298 Neighboring gene predicted gene, 30464 Neighboring gene predicted gene, 30519

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Activin A Determines Steroid Levels and Composition in the Fetal Testis. Whiley PAF, et al. Endocrinology, 2020 Jul 1. PMID 32274496
    2. Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Shalom-Barak T, et al. Dev Biol, 2012 Dec 1. PMID 22967998, Free PMC Article
    3. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Tamplin OJ, et al. Dev Biol, 2011 Dec 15. PMID 22008794
    4. Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Lumayag S, et al. Proc Natl Acad Sci U S A, 2013 Feb 5. PMID 23341629, Free PMC Article
    5. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein sel-1 homolog 3
    Names
    sel-1L3
    suppressor of lin-12-like protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172710.3 → NP_766298.2  protein sel-1 homolog 3

      See identical proteins and their annotated locations for NP_766298.2

      Status: VALIDATED

      Source sequence(s)
      AK122362, BC094607, BP769904
      Consensus CDS
      CCDS51501.1
      UniProtKB/Swiss-Prot
      E9QPJ6, Q148Y5, Q505D2, Q80TS8, Q8BMN0, Q8BYY3, Q8R0K7
      Related
      ENSMUSP00000031090.7, ENSMUST00000031090.8
      Conserved Domains (4) summary
      smart00671
      Location:801 → 839
      SEL1; Sel1-like repeats
      COG0790
      Location:612 → 853
      TPR; TPR repeat [Signal transduction mechanisms]
      sd00010
      Location:714 → 744
      SLR; SLR repeat [structural motif]
      pfam08238
      Location:736 → 766
      Sel1; Sel1 repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      53264425..53370794 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011240730.2 → XP_011239032.1  protein sel-1 homolog 3 isoform X1

      See identical proteins and their annotated locations for XP_011239032.1

      UniProtKB/Swiss-Prot
      Q80TS8
      Conserved Domains (2) summary
      COG0790
      Location:454 → 695
      TPR; TPR repeat [Signal transduction mechanisms]
      sd00010
      Location:556 → 586
      SLR; SLR repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q80TS8.3 GenPept UniProtKB/Swiss-Prot:Q80TS8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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