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    Fggy FGGY carbohydrate kinase domain containing [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298250, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fggyprovided by RGD
    Official Full Name
    FGGY carbohydrate kinase domain containingprovided by RGD
    Primary source
    RGD:1359429
    See related
    EnsemblRapid:ENSRNOG00000008907 AllianceGenome:RGD:1359429
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable D-ribulokinase activity. Predicted to be involved in carbohydrate phosphorylation; neuron cellular homeostasis; and pentose metabolic process. Predicted to be active in cytoplasm. Orthologous to human FGGY (FGGY carbohydrate kinase domain containing). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 76.7), Kidney (RPKM 62.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fggy in Genome Data Viewer
    Location:
    5q33
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (115514573..115901713)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (110398866..110786019)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (114516860..114901571)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120102924 Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC103692418 Neighboring gene uncharacterized LOC120102925 Neighboring gene hook microtubule-tethering protein 1 Neighboring gene cytochrome P450 2J3-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Whole-genome analysis of sporadic amyotrophic lateral sclerosis. Dunckley T, et al. N Engl J Med, 2007 Aug 23. PMID 17671248
    2. Molecular Identification of d-Ribulokinase in Budding Yeast and Mammals. Singh C, et al. J Biol Chem, 2017 Jan 20. PMID 27909055, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC94804

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables D-ribulokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in carbohydrate phosphorylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in neuron cellular homeostasis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in pentose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    FGGY carbohydrate kinase domain-containing protein
    NP_001013954.2
    XP_006238472.1
    XP_017448749.1
    XP_017448750.1
    XP_038965461.1
    XP_038965462.2
    XP_038965464.1
    XP_063143446.1
    XP_063143447.1
    XP_063143448.1
    XP_063143449.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013932.2 → NP_001013954.2  FGGY carbohydrate kinase domain-containing protein

      See identical proteins and their annotated locations for NP_001013954.2

      Status: VALIDATED

      Source sequence(s)
      BC090077, CB316436
      UniProtKB/TrEMBL
      F1LSP9
      Conserved Domains (1) summary
      cd07782
      Location:11 → 545
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      115514573..115901713
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017593260.3 → XP_017448749.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F1LSP9
      Related
      ENSRNOP00000011767.6, ENSRNOT00000011767.7
      Conserved Domains (1) summary
      cd07782
      Location:11 → 545
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    2. XM_017593261.3 → XP_017448750.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F1LSP9
      Conserved Domains (1) summary
      cd07782
      Location:11 → 545
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    3. XM_063287376.1 → XP_063143446.1  FGGY carbohydrate kinase domain-containing protein isoform X3

      UniProtKB/TrEMBL
      F1LSP9
      Related
      ENSRNOP00000109575.1, ENSRNOT00000145188.1

    4. XM_039109534.2 → XP_038965462.2  FGGY carbohydrate kinase domain-containing protein isoform X2

      UniProtKB/TrEMBL
      A0A8I6AN02

    5. XM_039109533.2 → XP_038965461.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F1LSP9
      Related
      ENSRNOP00000098720.1, ENSRNOT00000126021.1
      Conserved Domains (1) summary
      cd07782
      Location:11 → 545
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    6. XM_006238410.5 → XP_006238472.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      See identical proteins and their annotated locations for XP_006238472.1

      UniProtKB/TrEMBL
      F1LSP9
      Conserved Domains (1) summary
      cd07782
      Location:11 → 545
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    7. XM_039109536.2 → XP_038965464.1  FGGY carbohydrate kinase domain-containing protein isoform X5

      UniProtKB/TrEMBL
      A6JRI3
      Conserved Domains (1) summary
      cl17037
      Location:2 → 336
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    8. XM_063287379.1 → XP_063143449.1  FGGY carbohydrate kinase domain-containing protein isoform X6

    9. XM_063287378.1 → XP_063143448.1  FGGY carbohydrate kinase domain-containing protein isoform X5

      UniProtKB/TrEMBL
      A6JRI3

    10. XM_063287377.1 → XP_063143447.1  FGGY carbohydrate kinase domain-containing protein isoform X4

    RNA

    1. XR_010066354.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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