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    Ptx4 pentraxin 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287130, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ptx4provided by RGD
    Official Full Name
    pentraxin 4provided by RGD
    Primary source
    RGD:1311190
    See related
    EnsemblRapid:ENSRNOG00000060934 AllianceGenome:RGD:1311190
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311190
    Summary
    Orthologous to human PTX4 (pentraxin 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 10.4), Heart (RPKM 1.1) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ptx4 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (14644501..14650185)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14140028..14146163)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (14481044..14486277)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene intraflagellar transport 140 Neighboring gene transmembrane protein 204 Neighboring gene telomere maintenance 2 Neighboring gene chloride voltage-gated channel 7 Neighboring gene coiled-coil domain containing 154

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Long-term treatment with antidepressants, but not environmental stimulation, induces expression of NP2 mRNA in hippocampus and medial habenula. Bjartmar L, et al. Brain Res, 2010 Apr 30. PMID 20223226

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    pentraxin-4
    Names
    pentraxin 4, long

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      14644501..14650185
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_220237.6 → XP_220237.4  pentraxin-4

      See identical proteins and their annotated locations for XP_220237.4

      UniProtKB/TrEMBL
      A0A0G2JZ18
      Related
      ENSRNOP00000070878.3, ENSRNOT00000091072.3
      Conserved Domains (2) summary
      cl12013
      Location:57 → 194
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
      cl22861
      Location:289 → 488
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    Nucleotide Protein Strain
    Heading Accession and Version

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