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    Dipk1b divergent protein kinase domain 1B [ Mus musculus (house mouse) ]

    Gene ID: 56279, updated on 9-Dec-2024

    Summary

    Official Symbol
    Dipk1bprovided by MGI
    Official Full Name
    divergent protein kinase domain 1Bprovided by MGI
    Primary source
    MGI:MGI:1927576
    See related
    Ensembl:ENSMUSG00000036186 AllianceGenome:MGI:1927576
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PIP49; Fam69b; B230317C12Rik
    Summary
    Predicted to be located in endoplasmic reticulum membrane. Is expressed in early conceptus and secondary oocyte. Orthologous to human DIPK1B (divergent protein kinase domain 1B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 33.9), CNS E18 (RPKM 33.2) and 23 other tissues See more
    Orthologs
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    Genomic context

    See Dipk1b in Genome Data Viewer
    Location:
    2 A3; 2 18.97 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (26518469..26526509)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (26628457..26636497)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 2 Neighboring gene STARR-seq mESC enhancer starr_03989 Neighboring gene predicted gene, 39772 Neighboring gene small nucleolar RNA, H/ACA box 43 Neighboring gene small nucleolar RNA host gene 7 Neighboring gene small nucleolar RNA, H/ACA box 17

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 

    General gene information

    Markers

    Potential readthrough

    Included gene: Egfl7

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    divergent protein kinase domain 1B
    Names
    family with sequence similarity 69, member B
    pancreatitis-induced protein 49
    protein FAM69B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019833.3NP_062807.2  divergent protein kinase domain 1B

      See identical proteins and their annotated locations for NP_062807.2

      Status: VALIDATED

      Source sequence(s)
      AI840756, AK045880
      Consensus CDS
      CCDS50542.1
      UniProtKB/Swiss-Prot
      Q0VG43, Q80UM6, Q99ML4, Q9JMG0
      Related
      ENSMUSP00000073860.4, ENSMUST00000074240.4
      Conserved Domains (2) summary
      pfam12260
      Location:198399
      PIP49_C; Protein-kinase domain of FAM69
      pfam14875
      Location:23179
      PIP49_N; N-term cysteine-rich ER, FAM69

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      26518469..26526509
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)