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    Hou Houki [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32852, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Houprovided by FlyBase
    Official Full Name
    Houkiprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030944
    Locus tag
    Dmel_CG6617
    See related
    AllianceGenome:FB:FBgn0030944
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Posey180; CG6617; Dmel\CG6617
    Summary
    Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including antennal primordium; central brain primordium; embryonic/larval midgut; ganglia; and head epidermis primordium. Orthologous to human GID8 (GID complex subunit 8 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Hou in Genome Data Viewer
    Location:
    17C7-17C7; 1-60 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (18649396..18650444, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (18543429..18544477, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene wengen Neighboring gene Rab11 interacting protein Neighboring gene Nucleoporin 35kDa Neighboring gene Inhibitor of growth family, member 3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling. Kanda H, et al. J Biol Chem, 2002 Aug 9. PMID 12084706
    2. The E2 Marie Kondo and the CTLH E3 ligase clear deposited RNA binding proteins during the maternal-to-zygotic transition. Zavortink M, et al. Elife, 2020 Jun 23. PMID 32573431, Free PMC Article
    3. An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP. Fiedler M, et al. Elife, 2015 Aug 27. PMID 26312500, Free PMC Article
    4. Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cao WX, et al. Cell Rep, 2020 Jun 23. PMID 32579915, Free PMC Article
    5. Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster. Przewloka MR, et al. PLoS One, 2007 May 30. PMID 17534428, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    houki
    Names
    CG6617-PA
    Hou-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      18649396..18650444 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_133087.3 → NP_573315.1  houki [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573315.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VWS1
      Related
      FBpp0074386
      Conserved Domains (2) summary
      pfam08513
      Location:28 → 52
      LisH
      pfam10607
      Location:67 → 205
      CLTH; CTLH/CRA C-terminal to LisH motif domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VWS1 Q9VWS1

    Gene LinkOut

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