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    CG7139 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40448, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7139provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0027532
    Locus tag
    Dmel_CG7139
    See related
    AllianceGenome:FB:FBgn0027532
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.415; BcDNA:LD21293; Dmel\CG7139; mdcds_30855
    Summary
    Predicted to enable DNA endonuclease activity. Is expressed in organism. Orthologous to human N4BP2 (NEDD4 binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7139 in Genome Data Viewer
    Location:
    79B2-79B2; 3-47 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (22067270..22071848, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (22060344..22064948, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Octopamine-Tyramine receptor Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43995 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HemK2 functions for sufficient protein synthesis and RNA stability through eRF1 methylation during Drosophila oogenesis. Xu F, et al. Development, 2024 Jul 15. PMID 38881530
    2. Heterochromatic genes in Drosophila: a comparative analysis of two genes. Schulze SR, et al. Genetics, 2006 Jul. PMID 16648646, Free PMC Article
    3. A genetic toolkit for tagging intronic MiMIC containing genes. Nagarkar-Jaiswal S, et al. Elife, 2015 Jun 23. PMID 26102525, Free PMC Article
    4. Neurological proteins are not enriched for repetitive sequences. Huntley MA, et al. Genetics, 2004 Mar. PMID 15082536, Free PMC Article
    5. Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. Dottorini T, et al. BMC Bioinformatics, 2011 Jan 26. PMID 21269436, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA endonuclease activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables endonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7139-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      22067270..22071848 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141121.4 → NP_649378.1  uncharacterized protein Dmel_CG7139 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649378.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XZ11
      Related
      FBpp0078139
      Conserved Domains (5) summary
      smart00463
      Location:877 → 960
      SMR; Small MutS-related domain
      pfam08590
      Location:812 → 868
      DUF1771; Domain of unknown function (DUF1771)
      pfam13671
      Location:105 → 245
      AAA_33; AAA domain
      cl14813
      Location:606 → 707
      GluZincin; Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
      cl17190
      Location:105 → 277
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q86NY0 Q86NY0
    Q9XZ11 Q9XZ11

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