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    TotB Turandot B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42474, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TotBprovided by FlyBase
    Official Full Name
    Turandot Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038838
    Locus tag
    Dmel_CG5609
    See related
    AllianceGenome:FB:FBgn0038838
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LP06769; CG5609; Dmel\CG5609; tot; Tot B; TOTB
    Summary
    Involved in cellular response to UV; cellular response to heat; and response to bacterium. Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See TotB in Genome Data Viewer
    Location:
    93A2-93A2; 3-69 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20873938..20874522)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16699660..16700244)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Turandot A Neighboring gene Turandot C Neighboring gene long non-coding RNA:CR44048 Neighboring gene Turandot Z

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Exploring cross-protective effects between cold and immune stress in Drosophila melanogaster. Wiil J, et al. Parasite, 2023. PMID 38084935, Free PMC Article
    2. Anti-Tumor Effect of Turandot Proteins Induced via the JAK/STAT Pathway in the mxc Hematopoietic Tumor Mutant in Drosophila. Kinoshita Y, et al. Cells, 2023 Aug 11. PMID 37626857, Free PMC Article
    3. Trans-regulatory changes underpin the evolution of the Drosophila immune response. Ding SD, et al. PLoS Genet, 2022 Nov. PMID 36342922, Free PMC Article
    4. A family of Turandot-related genes in the humoral stress response of Drosophila. Ekengren S, et al. Biochem Biophys Res Commun, 2001 Jun 22. PMID 11409894
    5. A humoral stress response protects Drosophila tissues from antimicrobial peptides. Rommelaere S, et al. Curr Biol, 2024 Apr 8. PMID 38484734

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in cellular response to UV IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in immune system process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to UV IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to heat IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    turandot B
    Names
    CG5609-PA
    TotB-PA
    turandot

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      20873938..20874522
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079698.3 → NP_524422.1  turandot B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524422.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q962E0, Q9VDH4
      Related
      FBpp0083380
      Conserved Domains (1) summary
      pfam07240
      Location:41 → 116
      Turandot; Stress-inducible humoral factor Turandot
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VDH4.1 Q9VDH4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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