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    tth toothrin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32318, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tthprovided by FlyBase
    Official Full Name
    toothrinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030502
    Locus tag
    Dmel_CG12175
    See related
    AllianceGenome:FB:FBgn0030502
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:fe2G7; CG12175; Dmel\CG12175
    Summary
    Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See tth in Genome Data Viewer
    Location:
    12A8-12A8; 1-44 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13613193..13616586, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13507226..13510619, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ndc80 Neighboring gene BthD selenoprotein Neighboring gene Transport and Golgi organization 2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Overexpression of a novel gene toothrin in Drosophila]. Simonova OB, et al. Genetika, 2005 Feb. PMID 15810609
    2. In vivo analysis reveals that ATP-hydrolysis couples remodeling to SWI/SNF release from chromatin. Tilly BC, et al. Elife, 2021 Jul 27. PMID 34313222, Free PMC Article
    3. Understanding microcephaly through the study of centrosome regulation in Drosophila neural stem cells. Robinson BV, et al. Biochem Soc Trans, 2020 Oct 30. PMID 32897294, Free PMC Article
    4. A screen for fast evolving genes from Drosophila. Schmid KJ, et al. Proc Natl Acad Sci U S A, 1997 Sep 2. PMID 9275195, Free PMC Article
    5. Identification of Drosophila gene products required for phagocytosis of Candida albicans. Stroschein-Stevenson SL, et al. PLoS Biol, 2006 Jan. PMID 16336044, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    toothrin
    Names
    CG12175-PB
    CG12175-PC
    anon-fast-evolving-2G7
    toothreen
    tth-PB
    tth-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      13613193..13616586 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298287.1 → NP_001285216.1  toothrin, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285216.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYA9
      Conserved Domains (1) summary
      pfam14051
      Location:24 → 94
      Requiem_N; N-terminal domain of DPF2/REQ

    2. NM_132676.4 → NP_572904.1  toothrin, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572904.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYA9
      Related
      FBpp0073680
      Conserved Domains (1) summary
      pfam14051
      Location:24 → 94
      Requiem_N; N-terminal domain of DPF2/REQ
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T9L1 Q8T9L1
    Q9VYA9 Q9VYA9

    Gene LinkOut

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