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    Desi Desiccate [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41292, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Desiprovided by FlyBase
    Official Full Name
    Desiccateprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037832
    Locus tag
    Dmel_CG14686
    See related
    AllianceGenome:FB:FBgn0037832
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14686; Dmel\CG14686
    Summary
    Predicted to enable PDZ domain binding activity and SH2 domain binding activity. Involved in response to desiccation and sensory perception of taste. Located in apical part of cell. Is expressed in several structures, including assembly zone; embryonic/larval mouth; epidermis; labellar cap; and sense organ. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Desi in Genome Data Viewer
    Location:
    86C6-86C6; 3-50 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10779569..10780825)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6605291..6606547)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Chromosome associated protein H2 Neighboring gene Transcription factor TFIIFbeta Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene fau Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein L37

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Function of desiccate in gustatory sensilla of drosophila melanogaster. Kawano T, et al. Sci Rep, 2015 Nov 27. PMID 26610608, Free PMC Article
    2. Identification of a gene, Desiccate, contributing to desiccation resistance in Drosophila melanogaster. Kawano T, et al. J Biol Chem, 2010 Dec 10. PMID 20937803, Free PMC Article
    3. Genetic architecture of natural variation in cuticular hydrocarbon composition in Drosophila melanogaster. Dembeck LM, et al. Elife, 2015 Nov 14. PMID 26568309, Free PMC Article
    4. Correlation between desiccation stress response and epigenetic modifications of genes in Drosophila melanogaster: An example of environment-epigenome interaction. Sharma V, et al. Biochim Biophys Acta Gene Regul Mech, 2017 Oct. PMID 28801151
    5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables PDZ domain binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables SH2 domain binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to desiccation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory perception of taste IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical part of cell IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    desiccate
    Names
    CG14686-PA
    Desi-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      10779569..10780825
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141759.4 → NP_650016.1  desiccate [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650016.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VGX0
      Related
      FBpp0081751
      Conserved Domains (1) summary
      pfam07841
      Location:142 → 226
      DM4_12; DM4/DM12 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VGX0 Q9VGX0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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