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    be ben [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32430, updated on 9-Dec-2024

    Summary

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    Official Symbol
    beprovided by FlyBase
    Official Full Name
    benprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052594
    Locus tag
    Dmel_CG32594
    See related
    AllianceGenome:FB:FBgn0052594
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:CL1a5; BEST:LD10566; CG15026; CG32594; CG5530; Dmel\CG32594; E
    Summary
    Involved in long-term memory and neuromuscular synaptic transmission. Is expressed in several structures, including adult brain; head; mesectoderm; mesoderm anlage; and midline primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    Location:
    13A5-13A5; 1-49 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15024436..15042060)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (14918469..14936093)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ether a go-go Neighboring gene highwire Neighboring gene uncharacterized protein Neighboring gene NADH dehydrogenase (ubiquinone) B18 subunit Neighboring gene opossum

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ben Functions with scamp during synaptic transmission and long-term memory formation in Drosophila. Zhao H, et al. J Neurosci, 2009 Jan 14. PMID 19144841, Free PMC Article
    2. Highwire function at the Drosophila neuromuscular junction: spatial, structural, and temporal requirements. Wu C, et al. J Neurosci, 2005 Oct 19. PMID 16237161, Free PMC Article
    3. Highwire regulates synaptic growth in Drosophila. Wan HI, et al. Neuron, 2000 May. PMID 10839352
    4. Identification of novel genes in Drosophila reveals the complex regulation of early gene activity in the mesoderm. Casal J, et al. Proc Natl Acad Sci U S A, 1996 Sep 17. PMID 8816799, Free PMC Article
    5. Expansion and evolution of insect GMC oxidoreductases. Iida K, et al. BMC Evol Biol, 2007 May 11. PMID 17498303, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    mobile_element

    • Loc: 15034147-15041616 mobile_element_type = transposon:rover{}133

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in long-term memory IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in neuromuscular synaptic transmission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    ben
    Names
    CG32594-PB
    CG32594-PC
    CG32594-PF
    E protein
    be-PB
    be-PC
    be-PF
    gene A

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15024436..15042060
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132762.4 → NP_572990.2  ben, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572990.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N2Q1, Q9VXZ4
      Related
      FBpp0073773

    2. NM_167424.2 → NP_727817.1  ben, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727817.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRG2, Q9VXZ3
      Related
      FBpp0073774
      Conserved Domains (2) summary
      pfam06484
      Location:614 → 754
      Ten_N; Teneurin Intracellular Region
      pfam13229
      Location:270 → 408
      Beta_helix; Right handed beta helix region

    3. NM_001258745.2 → NP_001245674.1  ben, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245674.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRG2, Q9VXZ3
      Conserved Domains (2) summary
      pfam06484
      Location:614 → 754
      Ten_N; Teneurin Intracellular Region
      pfam13229
      Location:270 → 408
      Beta_helix; Right handed beta helix region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MRG2 Q8MRG2
    Q9N2Q1 Q9N2Q1
    Q9N2Q2 Q9N2Q2
    Q9VXZ3 Q9VXZ3
    Q9VXZ4 Q9VXZ4

    Gene LinkOut

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