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    TwdlR TweedleR [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318586, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TwdlRprovided by FlyBase
    Official Full Name
    TweedleRprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051081
    Locus tag
    Dmel_CG31081
    See related
    AllianceGenome:FB:FBgn0051081
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14240; CG14241; CG31081; Dmel\CG31081
    Summary
    Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in body morphogenesis and chitin-based cuticle development. Predicted to be located in extracellular matrix. Predicted to be active in chitin-based extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See TwdlR in Genome Data Viewer
    Location:
    97C2-97C2; 3-91 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26634885..26635998)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (22460607..22461720)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene TweedleN Neighboring gene TweedleH Neighboring gene TweedleS Neighboring gene long non-coding RNA:CR46233

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional changes revealed genes and pathways involved in the deficient testis caused by the inhibition of alkaline ceramidase (Dacer) in Drosophila melanogaster. Zhang MJ, et al. Arch Insect Biochem Physiol, 2021 Mar. PMID 33590535
    2. Transcriptomic Insights into the Insect Immune Response to Nematode Infection. Eleftherianos I, et al. Genes (Basel), 2021 Jan 30. PMID 33573306, Free PMC Article
    3. Annotation and analysis of low-complexity protein families of Anopheles gambiae that are associated with cuticle. Cornman RS, et al. Insect Mol Biol, 2009 Oct. PMID 19754739, Free PMC Article
    4. Viruses in Laboratory Drosophila and Their Impact on Host Gene Expression. Kuyateh O, et al. Viruses, 2023 Aug 31. PMID 37766256, Free PMC Article
    5. Molecular evolution of Drosophila cuticular protein genes. Cornman RS. PLoS One, 2009 Dec 17. PMID 20019874, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based cuticle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables structural constituent of chitin-based larval cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in body morphogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in chitin-based cuticle development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chitin-based cuticle development ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in chitin-based extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    TweedleR
    Names
    CG31081-PA
    TwdlR-PA
    tweedle

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      26634885..26635998
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170282.2 → NP_733161.2  TweedleR [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733161.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      D4G7C8, Q8IMR6
      Related
      FBpp0084405
      Conserved Domains (1) summary
      pfam03103
      Location:69 → 165
      DUF243; Domain of unknown function (DUF243)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IMR6 Q8IMR6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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