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    CG2021 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38229, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2021provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035271
    Locus tag
    Dmel_CG2021
    See related
    AllianceGenome:FB:FBgn0035271
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2021; l(3)62Be; l(3)neo7; neo7
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of precatalytic spliceosome. Is expressed in embryonic/larval lymph gland; embryonic/larval salivary gland; eye disc; larval central nervous system; and larval ventral nerve cord. Orthologous to human LSM8 (LSM8 homolog, U6 small nuclear RNA associated). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2021 in Genome Data Viewer
    Location:
    62B4-62B4; 3-1.0 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1777010..1777411, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1777010..1777411, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Dynein heavy chain at 62B Neighboring gene antisense RNA:CR44351 Neighboring gene uncharacterized protein Neighboring gene DNA polymerase delta subunit 2 Neighboring gene alpha Spectrin Neighboring gene mitochondrial ribosomal protein L46 Neighboring gene antisense RNA:CR45834

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell shape and interaction defects in alpha-spectrin mutants of Drosophila melanogaster. Lee JK, et al. J Cell Biol, 1993 Dec. PMID 8276898, Free PMC Article
    2. The genetics of the Dras3-Roughened-ecdysoneless chromosomal region (62B3-4 to 62D3-4) in Drosophila melanogaster: analysis of recessive lethal mutations. Sliter TJ, et al. Genetics, 1989 Oct. PMID 2511069, Free PMC Article
    3. D-Titin: a giant protein with dual roles in chromosomes and muscles. Machado C, et al. J Cell Biol, 2000 Oct 30. PMID 11062264, Free PMC Article
    4. Mapping a mutator, mu2, which increases the frequency of terminal deletions in Drosophila melanogaster. Wang M, et al. Mol Gen Genet, 1994 Dec 1. PMID 7808410
    5. The asymmetrically segregating lncRNA cherub is required for transforming stem cells into malignant cells. Landskron L, et al. Elife, 2018 Mar 27. PMID 29580384, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U4/U6 x U5 tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of U6 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U6 snRNP IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of U6 snRNP NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of precatalytic spliceosome HDA PubMed 
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small nuclear ribonucleoprotein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2021-PA
    lethal (3) 62Be

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1777010..1777411 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139403.2 → NP_647660.1  uncharacterized protein Dmel_CG2021 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647660.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W087
      Related
      FBpp0072674
      Conserved Domains (1) summary
      cd01727
      Location:1 → 91
      LSm8; Like-Sm protein 8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W087 Q9W087

    Gene LinkOut

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