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    CG4069 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39437, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4069provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036301
    Locus tag
    Dmel_CG4069
    See related
    AllianceGenome:FB:FBgn0036301
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0172774.58; Dmel\CG4069
    Summary
    Is expressed in several structures, including anterior endoderm; dorsal pharyngeal muscle cell; embryonic/larval midgut primordium; gut section; and mesoderm. Orthologous to human KLHDC4 (kelch domain containing 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4069 in Genome Data Viewer
    Location:
    69C6-69C6; 3-38 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12535426..12537315, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12528526..12530415, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Transferrin 2 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43612 Neighboring gene Phosphomannomutase type 2 Neighboring gene sosondowah Neighboring gene araucan

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Heat shock protein 83 (Hsp83) facilitates methoprene-tolerant (Met) nuclear import to modulate juvenile hormone signaling. He Q, et al. J Biol Chem, 2014 Oct 3. PMID 25122763, Free PMC Article
    2. Comparative interactome analysis of α-arrestin families in human and Drosophila. Lee KT, et al. Elife, 2024 Jan 25. PMID 38270169, Free PMC Article
    3. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article
    4. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4069-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12535426..12537315 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140333.3 → NP_648590.1  uncharacterized protein Dmel_CG4069 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648590.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTZ7
      Related
      FBpp0075697
      Conserved Domains (4) summary
      sd00038
      Location:69 → 120
      Kelch; KELCH repeat [structural motif]
      pfam07646
      Location:237 → 297
      Kelch_2; Kelch motif
      pfam13415
      Location:80 → 132
      Kelch_3; Galactose oxidase, central domain
      pfam13854
      Location:423 → 463
      Kelch_5; Kelch motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTZ7 Q9VTZ7

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