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    Cpr62Bc Cuticular protein 62Bc [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38241, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cpr62Bcprovided by FlyBase
    Official Full Name
    Cuticular protein 62Bcprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035281
    Locus tag
    Dmel_CG1919
    See related
    AllianceGenome:FB:FBgn0035281
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1919; DmelCpr62Bc; Dmel\CG1919
    Summary
    Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be located in chitin-based extracellular matrix. Predicted to be active in extracellular matrix. Is expressed in several structures, including adult head; embryonic epipharynx; embryonic head epidermis; epidermis; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cpr62Bc in Genome Data Viewer
    Location:
    62B7-62B7; 3-1.0 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1840281..1842084, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1840281..1842084, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 62Ba Neighboring gene Cuticular protein 62Bb Neighboring gene CNMamide Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extensive gene amplification and concerted evolution within the CPR family of cuticular proteins in mosquitoes. Cornman RS, et al. Insect Biochem Mol Biol, 2008 Jun. PMID 18510978, Free PMC Article
    2. High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae. Wang M, et al. Dev Cell, 2022 May 23. PMID 35512700
    3. [Identification of C(2)M interacting proteins by yeast two-hybrid screening]. Yue SS, et al. Yi Chuan, 2015 Nov. PMID 26582530
    4. Elucidating the "Gravome": Quantitative Proteomic Profiling of the Response to Chronic Hypergravity in Drosophila. Hosamani R, et al. J Proteome Res, 2016 Dec 2. PMID 27648494
    5. Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy. Yatsenko AS, et al. BMC Med, 2020 Jan 21. PMID 31959160, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based larval cuticle ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chitin-based extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cuticular protein 62Bc
    Names
    CG1919-PA
    CG1919-PB
    Cpr62Bc-PA
    Cpr62Bc-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1840281..1842084 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139411.2 → NP_647668.1  cuticular protein 62Bc, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647668.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W077
      Related
      FBpp0072748
      Conserved Domains (1) summary
      pfam00379
      Location:54 → 106
      Chitin_bind_4; Insect cuticle protein

    2. NM_001274364.1 → NP_001261293.1  cuticular protein 62Bc, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261293.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W077
      Conserved Domains (1) summary
      pfam00379
      Location:54 → 106
      Chitin_bind_4; Insect cuticle protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W077 Q9W077

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