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    CG9550 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33913, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9550provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031826
    Locus tag
    Dmel_CG9550
    See related
    AllianceGenome:FB:FBgn0031826
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    d6ST2; Dmel\CG9550
    Summary
    Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process and sulfur compound metabolic process. Is expressed in adult head. Human ortholog(s) of this gene implicated in macular corneal dystrophy; osteochondrodysplasia; and spondyloepiphyseal dysplasia with congenital joint dislocations. Orthologous to several human genes including CHST3 (carbohydrate sulfotransferase 3) and CHST5 (carbohydrate sulfotransferase 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9550 in Genome Data Viewer
    Location:
    26D9-26D9; 2-20 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6497053..6498466)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6497053..6498466)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Coat Protein (coatomer) epsilon Neighboring gene uncharacterized protein Neighboring gene PHD finger protein 5a Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44775 Neighboring gene eyes absent

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Epi-MEIF: detecting higher order epistatic interactions for complex traits using mixed effect conditional inference forests. Saha S, et al. Nucleic Acids Res, 2022 Oct 28. PMID 36107776, Free PMC Article
    2. Ectopic expression screen identifies genes affecting Drosophila mesoderm development including the HSPG Trol. Trisnadi N, et al. G3 (Bethesda), 2014 Dec 23. PMID 25538103, Free PMC Article
    3. Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing. Yamamoto-Hino M, et al. Genes Cells, 2015 Jun. PMID 25940448, Free PMC Article
    4. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables N-acetylglucosamine 6-O-sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in N-acetylglucosamine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sulfur compound metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9550-PA
    NP_609042.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      6497053..6498466
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135198.2 → NP_609042.1  uncharacterized protein Dmel_CG9550 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609042.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZD1, Q9VMC4
      Related
      FBpp0078916
      Conserved Domains (1) summary
      cl21551
      Location:196 → 340
      Sulfotransfer_1; Sulfotransferase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MZD1 Q8MZD1
    Q9VMC4 Q9VMC4

    Gene LinkOut

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