U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG3505 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41777, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG3505provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038250
    Locus tag
    Dmel_CG3505
    See related
    AllianceGenome:FB:FBgn0038250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cSPH9; Dmel\CG3505; proPO-AE; SPH9
    Summary
    Predicted to be involved in innate immune response. Located in extracellular region. Is expressed in embryonic/larval fat body. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG3505 in Genome Data Viewer
    Location:
    88C10-88C10; 3-55 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14657447..14659228)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10483169..10484950)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cadherin 88C Neighboring gene lethal (3) L1231 Neighboring gene Hexamethylene bisacetamide inducible Neighboring gene Rad17 Neighboring gene Histone H1 variant BigH1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A dual role for the dREAM/MMB complex in the regulation of differentiation-specific E2F/RB target genes. Lee H, et al. Mol Cell Biol, 2012 Jun. PMID 22451490, Free PMC Article
    2. Expression and regulation of Spätzle-processing enzyme in Drosophila. Mulinari S, et al. FEBS Lett, 2006 Oct 2. PMID 16996061
    3. Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes. Korenjak M, et al. Cell, 2004 Oct 15. PMID 15479636
    4. Drosophila RB proteins repress differentiation-specific genes via two different mechanisms. Lee H, et al. Mol Cell Biol, 2010 May. PMID 20176807, Free PMC Article
    5. Drosophila activating transcription factor-2 is involved in stress response via activation by p38, but not c-Jun NH(2)-terminal kinase. Sano Y, et al. Mol Biol Cell, 2005 Jun. PMID 15788564, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables serine-type endopeptidase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region HDA PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG3505-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14657447..14659228
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142123.3 → NP_650380.2  uncharacterized protein Dmel_CG3505 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650380.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SX54, Q9VFH3
      Related
      FBpp0082425
      Conserved Domains (3) summary
      smart00020
      Location:111 → 354
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:111 → 356
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam12032
      Location:30 → 82
      CLIP; Regulatory CLIP domain of proteinases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SX54 Q8SX54

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools