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    CG10948 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39459, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10948provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036317
    Locus tag
    Dmel_CG10948
    See related
    AllianceGenome:FB:FBgn0036317
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg10948; CT30663; Dmel\CG10948
    Summary
    Predicted to enable NADH dehydrogenase activity; mRNA binding activity; and protein disulfide isomerase activity. Predicted to be involved in ultradian rhythm. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including ENOX1 (ecto-NOX disulfide-thiol exchanger 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10948 in Genome Data Viewer
    Location:
    69E6-69E6; 3-39 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12844254..12850117, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12837354..12843217, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene nebulosa Neighboring gene WW domain binding protein 2 Neighboring gene Equilibrative nucleoside transporter 3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Discovery of insect and human dengue virus host factors. Sessions OM, et al. Nature, 2009 Apr 23. PMID 19396146, Free PMC Article
    2. Abdominal-B neurons control Drosophila virgin female receptivity. Bussell JJ, et al. Curr Biol, 2014 Jul 21. PMID 24998527, Free PMC Article
    3. Differential microarray analysis of Drosophila mushroom body transcripts using chemical ablation. Kobayashi M, et al. Proc Natl Acad Sci U S A, 2006 Sep 26. PMID 16971484, Free PMC Article
    4. Highly constrained intergenic Drosophila ultraconserved elements are candidate ncRNAs. Kern AD, et al. Genome Biol Evol, 2015 Jan 23. PMID 25618141, Free PMC Article
    5. Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila. Hansen KD, et al. PLoS Genet, 2009 Jun. PMID 19543372, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables NADH dehydrogenase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein disulfide isomerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in ultradian rhythm IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10948-PB
    CG10948-PC
    CG10948-PD
    NP_648606.2
    NP_729844.1
    NP_729845.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12844254..12850117 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140349.3 → NP_648606.2  uncharacterized protein Dmel_CG10948, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648606.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G7H842, Q8IQH5
      Related
      FBpp0075670
      Conserved Domains (2) summary
      COG0724
      Location:234 → 374
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12228
      Location:228 → 311
      RRM_ENOX; RNA recognition motif (RRM) in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

    2. NM_168524.2 → NP_729844.1  uncharacterized protein Dmel_CG10948, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729844.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VU18
      Related
      FBpp0075671
      Conserved Domains (2) summary
      COG0724
      Location:234 → 318
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12228
      Location:228 → 311
      RRM_ENOX; RNA recognition motif (RRM) in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

    3. NM_168525.3 → NP_729845.2  uncharacterized protein Dmel_CG10948, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729845.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQH4
      Conserved Domains (2) summary
      COG0724
      Location:227 → 311
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12228
      Location:221 → 304
      RRM_ENOX; RNA recognition motif (RRM) in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQH4 Q8IQH4
    Q8IQH5 Q8IQH5
    Q8SYY0 Q8SYY0
    Q9VU18 Q9VU18

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