yem yemanuclein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: yemprovided by FlyBase
Official Full Name: yemanucleinprovided by FlyBase
Primary source: FLYBASE:FBgn0005596
Locus tag: Dmel_CG14513
See related: AllianceGenome:FB:FBgn0005596
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG11879; CG14513; Dmel\CG14513; yem-alpha; yema; yemalpha; Yemalpha; yG4.5; yT4.5
Summary: Enables DNA binding activity. Involved in chromatin organization and female meiotic nuclear division. Located in germinal vesicle; kinetochore; and male pronucleus. Is expressed in several structures, including embryonic/larval midgut primordium; ganglia; germline cell; gonad; and head epidermis primordium. Orthologous to human UBN1 (ubinuclein 1) and UBN2 (ubinuclein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (29118330..29122879, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (24944052..24948601, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Intellectual disability-associated BRWD3 regulates gene expression through inhibition of HIRA/YEM-mediated chromatin deposition of histone H3.3.
Title: Intellectual disability-associated dBRWD3 regulates gene expression through inhibition of HIRA/YEM-mediated chromatin deposition of histone H3.3.
Drosophila Yemanuclein associates with the cohesin and synaptonemal complexes
Title: Drosophila Yemanuclein associates with the cohesin and synaptonemal complexes.
we demonstrate that HIRA and YEM proteins interact and are mutually dependent for their targeting to the decondensing male pronucleus.
Title: Drosophila Yemanuclein and HIRA cooperate for de novo assembly of H3.3-containing nucleosomes in the male pronucleus.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in chromatin organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in chromatin organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in female meiotic nuclear division	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in germinal vesicle	IDA Inferred from Direct Assay more info	PubMed
located_in kinetochore	IDA Inferred from Direct Assay more info	PubMed
located_in male pronucleus	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

Names: CG14513-PA; CG14513-PB; yem-PA; yem-PB; yem-alpha; yema nuclein alpha; yema-gene-4.5; yemalpha; yemanuclein alpha; yemanuclein-alpha

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The following sections contain reference sequences that belong to a specific genome build. Explain