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    sofe sister of feo [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32016, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sofeprovided by FlyBase
    Official Full Name
    sister of feoprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030242
    Locus tag
    Dmel_CG1655
    See related
    AllianceGenome:FB:FBgn0030242
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1655; Dmel\CG1655
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in mitotic spindle midzone assembly. Predicted to be active in cytoplasm and mitotic spindle midzone. Is expressed in wing hinge primordium and wing pouch. Orthologous to human PRC1 (protein regulator of cytokinesis 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See sofe in Genome Data Viewer
    Location:
    9F5-9F5; 1-33 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10855000..10857413, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10749033..10751446, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene fascetto Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Feo, the Drosophila homolog of PRC1, is required for central-spindle formation and cytokinesis. Vernì F, et al. Curr Biol, 2004 Sep 7. PMID 15341744
    2. Characteristics of molecular-genetic organization of intercalary heterochromatin band 10A1-2 in X chromosome of Drosophila melanogaster. Babenko VN, et al. Dokl Biochem Biophys, 2009 Jan-Feb. PMID 19341102
    3. The genetics of egg retention and fertilization success in Drosophila: One step closer to understanding the transition from facultative to obligate viviparity. Horváth B, et al. Evolution, 2018 Feb. PMID 29265369
    4. X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila. Legube G, et al. Genes Dev, 2006 Apr 1. PMID 16547175, Free PMC Article
    5. Post-mating gene expression profiles of female Drosophila melanogaster in response to time and to four male accessory gland proteins. McGraw LA, et al. Genetics, 2008 Jul. PMID 18562649, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitotic spindle midzone assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitotic spindle midzone IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in spindle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    sister of feo
    Names
    CG1655-PA
    CG1655-PB
    sofe-PA
    sofe-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10855000..10857413 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298163.1 → NP_001285092.1  sister of feo, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285092.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961S2, Q9VZ61
      Conserved Domains (1) summary
      pfam03999
      Location:36 → 598
      MAP65_ASE1; Microtubule associated protein (MAP65/ASE1 family)

    2. NM_132431.3 → NP_572659.2  sister of feo, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572659.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961S2, Q9VZ61
      Related
      FBpp0073265
      Conserved Domains (1) summary
      pfam03999
      Location:36 → 598
      MAP65_ASE1; Microtubule associated protein (MAP65/ASE1 family)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q961S2 Q961S2
    Q9VZ61 Q9VZ61

    Gene LinkOut

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