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    Cyp6a20 Cytochrome P450 6a20 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36664, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cyp6a20provided by FlyBase
    Official Full Name
    Cytochrome P450 6a20provided by FlyBase
    Primary source
    FLYBASE:FBgn0033980
    Locus tag
    Dmel_CG10245
    See related
    AllianceGenome:FB:FBgn0033980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    6a20; agg; CG10245; cyp6a20; CYP6a20; Dmel\CG10245; p450
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Involved in aggressive behavior and defense response to Gram-negative bacterium. Is expressed in adult fat body. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp6a20 in Genome Data Viewer
    Location:
    51D1-51D1; 2-73 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14882118..14884046)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10769623..10771551)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cytochrome P450 6a23 Neighboring gene Cytochrome P450 6a19 Neighboring gene Cytochrome P450 6a9 Neighboring gene Cytochrome P450 6a21 Neighboring gene Cytochrome P450 6a8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Exploring the Genetic Underpinnings of Aggression in Drosophila melanogaster. Takemori T. J Undergrad Neurosci Educ, 2021 Spring. PMID 34552446, Free PMC Article
    2. Early Life Experience Shapes Male Behavior and Social Networks in Drosophila. Bentzur A, et al. Curr Biol, 2021 Feb 8. PMID 33186552
    3. A common genetic target for environmental and heritable influences on aggressiveness in Drosophila. Wang L, et al. Proc Natl Acad Sci U S A, 2008 Apr 15. PMID 18408154, Free PMC Article
    4. Neurobiology. Fruit fly fight club. Miller G. Science, 2007 Jan 12. PMID 17218504
    5. Genetics of aggression. Anholt RR, et al. Annu Rev Genet, 2012. PMID 22934647

    See all (69) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Social experience increased Cyp6a20 expression and decreased aggressiveness in a reversible manner.
      Title: A common genetic target for environmental and heritable influences on aggressiveness in Drosophila.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in aggressive behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in defense response to Gram-negative bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome P450 6a20
    Names
    CG10245-PB
    Cyp6a20-PB
    NP_611002.3
    • frameshift

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14882118..14884046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137158.4 → NP_611002.3  cytochrome P450 6a20 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611002.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B5RJG1, Q95R69, Q9V773
      Conserved Domains (1) summary
      pfam00067
      Location:32 → 496
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V773.2 Q9V773

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials