ZnT77C Zinc transporter 77C [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: ZnT77Cprovided by FlyBase
Official Full Name: Zinc transporter 77Cprovided by FlyBase
Primary source: FLYBASE:FBgn0037000
Locus tag: Dmel_CG5130
See related: AllianceGenome:FB:FBgn0037000
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0118547.435; cg5130; CG5130; Dmel\CG5130; dZnT1h; dZnT77C; ZNT77C
Summary: Enables zinc efflux transmembrane transporter activity. Involved in detoxification of zinc ion and zinc ion transmembrane transport. Located in basolateral plasma membrane. Is expressed in several structures, including adult head; larval nervous system; larval ventral nerve cord; yolk; and yolk nucleus. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (20484293..20494921, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (20477393..20488021, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables monoatomic cation transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables zinc efflux transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables zinc ion transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion transmembrane transporter activity	IC Inferred by Curator more info	PubMed

Process	Evidence Code	Pubs
involved_in detoxification of zinc ion	IBA Inferred from Biological aspect of Ancestor more info
involved_in detoxification of zinc ion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intracellular zinc ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in monoatomic cation transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in zinc ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in zinc ion transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in basolateral plasma membrane	IDA Inferred from Direct Assay more info	PubMed
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain