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    CG10472 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38688, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10472provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035670
    Locus tag
    Dmel_CG10472
    See related
    AllianceGenome:FB:FBgn0035670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.101; Dmel\CG10472; SP78
    Summary
    Enables serine hydrolase activity. Predicted to be involved in innate immune response and proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10472 in Genome Data Viewer
    Location:
    65A5-65A5; 3-16 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6061372..6062910, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6054472..6056010, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene tantalus Neighboring gene long non-coding RNA:CR45441 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In Drosophila Hemolymph, Serine Proteases Are the Major Gelatinases and Caseinases. Gatti JL, et al. Insects, 2024 Mar 28. PMID 38667364, Free PMC Article
    2. Genomic responses to the socio-sexual environment in male Drosophila melanogaster exposed to conspecific rivals. Mohorianu I, et al. RNA, 2017 Jul. PMID 28428330, Free PMC Article
    3. Proteomic Analysis of Red Ginseng on Prolonging the Life Span of Male Drosophila melanogaster. Hou W, et al. Front Pharmacol, 2021. PMID 34177563, Free PMC Article
    4. Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging. Jiao J, et al. Cell Rep, 2023 Jan 31. PMID 36640359, Free PMC Article
    5. Fitness Analysis and Transcriptome Profiling Following Repeated Mild Heat Stress of Varying Frequency in Drosophilamelanogaster Females. Gruntenko NE, et al. Biology (Basel), 2021 Dec 14. PMID 34943239, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine hydrolase activity HDA PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10472-PA
    NP_648017.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6061372..6062910 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139760.2 → NP_648017.1  uncharacterized protein Dmel_CG10472 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648017.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MR67, Q9VRT2
      Related
      FBpp0076774
      Conserved Domains (2) summary
      smart00020
      Location:46 → 279
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:47 → 282
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MR67 Q8MR67
    Q9VRT2 Q9VRT2

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