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    CG1607 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43707, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1607provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039844
    Locus tag
    Dmel_CG1607
    See related
    AllianceGenome:FB:FBgn0039844
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg1607; Cg1607; Dmel\CG1607
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in membrane. Is expressed in adult abdomen; adult head; adult thorax; embryonic proventriculus; and wing disc. Human ortholog(s) of this gene implicated in lysinuric protein intolerance. Orthologous to several human genes including SLC7A8 (solute carrier family 7 member 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1607 in Genome Data Viewer
    Location:
    100C2-100C3; 3-102 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31382109..31391893)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27207831..27217615)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46118 Neighboring gene gasket Neighboring gene uncharacterized protein Neighboring gene UDP-glycosyltransferase family 35 member D1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Adipocyte amino acid sensing controls adult germline stem cell number via the amino acid response pathway and independently of Target of Rapamycin signaling in Drosophila. Armstrong AR, et al. Development, 2014 Dec. PMID 25359724, Free PMC Article
    2. Drosophila expresses a CD98 transporter with an evolutionarily conserved structure and amino acid-transport properties. Reynolds B, et al. Biochem J, 2009 May 27. PMID 19335336, Free PMC Article
    3. Nonvesicular release of glutamate by glial xCT transporters suppresses glutamate receptor clustering in vivo. Augustin H, et al. J Neurosci, 2007 Jan 3. PMID 17202478, Free PMC Article
    4. The negative elongation factor NELF promotes induced transcriptional response of Drosophila ecdysone-dependent genes. Mazina MY, et al. Sci Rep, 2021 Jan 8. PMID 33420323, Free PMC Article
    5. Genetics of cocaine and methamphetamine consumption and preference in Drosophila melanogaster. Highfill CA, et al. PLoS Genet, 2019 May. PMID 31107875, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1607-PA
    CG1607-PB
    CG1607-PC
    CG1607-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31382109..31391893
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143608.2 → NP_651865.1  uncharacterized protein Dmel_CG1607, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651865.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V9Y0
      Related
      FBpp0085146
      Conserved Domains (1) summary
      TIGR00911
      Location:42 → 500
      2A0308; L-type amino acid transporter

    2. NM_001276211.1 → NP_001263140.1  uncharacterized protein Dmel_CG1607, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001263140.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHK8
      Conserved Domains (1) summary
      TIGR00911
      Location:42 → 501
      2A0308; L-type amino acid transporter

    3. NM_170548.2 → NP_733427.1  uncharacterized protein Dmel_CG1607, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733427.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V9Y0
      Related
      FBpp0085147
      Conserved Domains (1) summary
      TIGR00911
      Location:42 → 500
      2A0308; L-type amino acid transporter

    4. NM_001276210.1 → NP_001263139.1  uncharacterized protein Dmel_CG1607, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001263139.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHK8
      Conserved Domains (1) summary
      TIGR00911
      Location:42 → 501
      2A0308; L-type amino acid transporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KHK8 A0A0B4KHK8
    Q95T33 Q95T33
    Q9V9Y0 Q9V9Y0

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