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    hzg herzog [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39748, updated on 9-Dec-2024

    Summary

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    Official Symbol
    hzgprovided by FlyBase
    Official Full Name
    herzogprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036556
    Locus tag
    Dmel_CG5830
    See related
    AllianceGenome:FB:FBgn0036556
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    24664944; CG5830; Dmel\CG5830
    Summary
    Enables phosphoprotein phosphatase activity. Involved in positive regulation of embryonic development. Located in plasma membrane. Is expressed in adult brain cell body rind; adult head; and adult mushroom body. Orthologous to several human genes including CTDSP1 (CTD small phosphatase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See hzg in Genome Data Viewer
    Location:
    72C1-72C2; 3-43 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15992669..16004736, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15985769..15997836, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45446 Neighboring gene DNA polymerase delta subunit 1 Neighboring gene Huntingtin-interacting protein 14 Neighboring gene mitochondrial ribosomal protein S31 Neighboring gene mind bomb 1 Neighboring gene long non-coding RNA:CR43950 Neighboring gene long non-coding RNA:CR45998

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phosphoprotein phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    herzog
    Names
    CG5830-PA
    CG5830-PB
    hzg-PA
    hzg-PB
    NP_001261912.1
    NP_648825.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15992669..16004736 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140568.3 → NP_648825.1  herzog, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648825.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VUX0
      Related
      FBpp0075276
      Conserved Domains (2) summary
      COG5190
      Location:78 → 253
      FCP1; TFIIF-interacting CTD phosphatase, includes NLI-interacting factor [Transcription]
      TIGR02251
      Location:89 → 247
      HIF-SF_euk; Dullard-like phosphatase domain

    2. NM_001274983.2 → NP_001261912.1  herzog, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261912.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      M9PFN0, Q7YU53, Q9VUX0
      Conserved Domains (1) summary
      TIGR02251
      Location:112 → 270
      HIF-SF_euk; Dullard-like phosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PFN0.1 M9PFN0

    Gene LinkOut

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