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    HipHop HP1-HOAP-interacting protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40047, updated on 9-Dec-2024

    Summary

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    Official Symbol
    HipHopprovided by FlyBase
    Official Full Name
    HP1-HOAP-interacting proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036815
    Locus tag
    Dmel_CG6874
    See related
    AllianceGenome:FB:FBgn0036815
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE10558; CG6874; Dmel\CG6874; hiphop; Hiphop; HIPHOP; l(3)neo26
    Summary
    Involved in CENP-A containing chromatin assembly and protection from non-homologous end joining at telomere. Located in chromosome, telomeric region. Is expressed in spermatocyte. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See HipHop in Genome Data Viewer
    Location:
    75E1-75E1; 3-45 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (18821171..18822353)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (18814271..18815453)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene ftz transcription factor 1 Neighboring gene long non-coding RNA:CR45939 Neighboring gene uncharacterized protein Neighboring gene Catalase Neighboring gene long non-coding RNA:CR32027 Neighboring gene I'm not dead yet

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Taming active transposons at Drosophila telomeres: The interconnection between HipHop's roles in capping and transcriptional silencing.
      Title: Taming active transposons at Drosophila telomeres: The interconnection between HipHop's roles in capping and transcriptional silencing.
    2. Overexpression of Hiphop increased the survival of somatic cells with broken chromosomes. In the male germline, Hiphop overexpression greatly increased the transmission of healed chromosomes.
      Title: Chromosome Healing Is Promoted by the Telomere Cap Component Hiphop in Drosophila.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in CENP-A containing chromatin assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protection from non-homologous end joining at telomere IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protection from non-homologous end joining at telomere IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in telomere capping IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome, telomeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    HP1-HOAP-interacting protein
    Names
    CG6874-PA
    CG6874-PB
    HP1 and HOAP-interacting protein
    HP1-HOAP interacting protein
    HipHop-PA
    HipHop-PB
    hiphop
    l(3)neo26
    lethal (3) neo26

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      18821171..18822353
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168777.2 → NP_730362.1  HP1-HOAP-interacting protein, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730362.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JWP6
      Related
      FBpp0074824

    2. NM_140804.3 → NP_649061.1  HP1-HOAP-interacting protein, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649061.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JWP6
      Related
      FBpp0074823
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JWP6 Q7JWP6

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