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    Obp49a Odorant-binding protein 49a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36399, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Obp49aprovided by FlyBase
    Official Full Name
    Odorant-binding protein 49aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050052
    Locus tag
    Dmel_CG30052
    See related
    AllianceGenome:FB:FBgn0050052
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH25962; CG30052; CG8769; DmelObp49a; Dmel\CG30052; obp49a; Obp49A; OBP49a
    Summary
    Predicted to enable odorant binding activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in extracellular region. Is expressed in labellar taste bristle and labellum. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Obp49a in Genome Data Viewer
    Location:
    49B12-49B12; 2-67 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12690059..12690955, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8577564..8578460, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Nucleoporin 188kDa Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Wake-up-call

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conservation of the behavioral and transcriptional response to social experience among Drosophilids. Shultzaberger RK, et al. Genes Brain Behav, 2019 Jan. PMID 29797548, Free PMC Article
    2. Allelic imbalance in Drosophila hybrid heads: exons, isoforms, and evolution. Graze RM, et al. Mol Biol Evol, 2012 Jun. PMID 22319150, Free PMC Article
    3. An odorant-binding protein required for suppression of sweet taste by bitter chemicals. Jeong YT, et al. Neuron, 2013 Aug 21. PMID 23972598, Free PMC Article
    4. Regulatory divergence in Drosophila melanogaster and D. simulans, a genomewide analysis of allele-specific expression. Graze RM, et al. Genetics, 2009 Oct. PMID 19667135, Free PMC Article
    5. "Plus-C" odorant-binding protein genes in two Drosophila species and the malaria mosquito Anopheles gambiae. Zhou JJ, et al. Gene, 2004 Feb 18. PMID 14960367

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study showed that Obp49a required for suppression of sweet taste by bitter chemicals.
      Title: An odorant-binding protein required for suppression of sweet taste by bitter chemicals.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Odorant-binding protein 49a
    Names
    CG30052-PA
    Obp49a-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12690059..12690955 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136968.2 → NP_610812.1  Odorant-binding protein 49a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610812.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JVM1
      Related
      FBpp0086985
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JVM1 Q7JVM1

    Gene LinkOut

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