Alg9 ALG9, alpha-1,2-mannosyltransferase [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Alg9provided by FlyBase
Official Full Name: ALG9, alpha-1,2-mannosyltransferaseprovided by FlyBase
Primary source: FLYBASE:FBgn0039293
Locus tag: Dmel_CG11851
See related: AllianceGenome:FB:FBgn0039293
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: alg9; CG11851; dAlg9; Dmel\CG11851
Summary: Predicted to enable dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity and dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity. Predicted to be involved in protein N-linked glycosylation. Located in endomembrane system. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Il. Orthologous to human ALG9 (ALG9 alpha-1,2-mannosyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (25221589..25224118)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (21047311..21049840)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables alpha-1,2-mannosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein N-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in endomembrane system	HDA more info	PubMed
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info

NP_651353.1

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The following sections contain reference sequences that belong to a specific genome build. Explain