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    CG32486 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38367, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32486provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0266918
    Locus tag
    Dmel_CG32486
    See related
    AllianceGenome:FB:FBgn0266918
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.267; CG14954; CG16745; Dmel\CG32486; l(2)SH3 095; l(3)SH095
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be active in nucleus. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; epithelium; ganglia; and mesoderm. Orthologous to human ZFTRAF1 (zinc finger TRAF-type containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32486 in Genome Data Viewer
    Location:
    63A5-63A6; 3-5 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3055908..3070839, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3055908..3070839, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Poly(A) specific ribonuclease subunit PAN3 Neighboring gene small nuclear RNA U5 at 63BC

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. De novo piRNA cluster formation in the Drosophila germ line triggered by transgenes containing a transcribed transposon fragment. Olovnikov I, et al. Nucleic Acids Res, 2013 Jun. PMID 23620285, Free PMC Article
    2. Nutritional control of gene expression in Drosophila larvae via TOR, Myc and a novel cis-regulatory element. Li L, et al. BMC Cell Biol, 2010 Jan 20. PMID 20089194, Free PMC Article
    3. Nodal points and complexity of Notch-Ras signal integration. Hurlbut GD, et al. Proc Natl Acad Sci U S A, 2009 Feb 17. PMID 19171888, Free PMC Article
    4. The evolution of constitutively active humoral immune defenses in Drosophila populations under high parasite pressure. Zhou SO, et al. PLoS Pathog, 2024 Jan. PMID 38206983, Free PMC Article
    5. A screen for E3 ubiquitination ligases that genetically interact with the adaptor protein Cindr during Drosophila eye patterning. Ketosugbo KF, et al. PLoS One, 2017. PMID 29117266, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32486-PD
    lethal (3) SH095

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      3055908..3070839 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139508.3 → NP_647765.1  uncharacterized protein Dmel_CG32486 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647765.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q960J5, Q9VZV5
      Related
      FBpp0072874
      Conserved Domains (2) summary
      pfam13920
      Location:109 → 164
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
      cl19105
      Location:168 → 232
      Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VZV5.2 Q9VZV5

    Gene LinkOut

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