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    Lrrc51 leucine rich repeat containing 51 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293156, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Lrrc51provided by RGD
    Official Full Name
    leucine rich repeat containing 51provided by RGD
    Primary source
    RGD:1565856
    See related
    EnsemblRapid:ENSRNOG00000020124 AllianceGenome:RGD:1565856
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565856
    Summary
    Predicted to be located in cytoplasm. Predicted to be active in axoneme. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 635.9) and Lung (RPKM 35.5) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lrrc51 in Genome Data Viewer
    Location:
    1q32
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (165690617..165709837, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (156278617..156297838, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (166997973..167017221, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene leucine rich transmembrane and O-methyltransferase domain containing Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Neighboring gene nuclear mitotic apparatus protein 1 Neighboring gene uncharacterized LOC134483764 Neighboring gene interleukin 18 binding protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Mutations of LRTOMT, a fusion gene with alternative reading frames, cause nonsyndromic deafness in humans. Ahmed ZM, et al. Nat Genet, 2008 Nov. PMID 18953341, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in axoneme IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 51
    Names
    protein LRTOMT1
    NP_001099754.1
    XP_006229932.1
    XP_006229933.1
    XP_006229934.1
    XP_006229935.1
    XP_006229936.1
    XP_006229937.1
    XP_063141282.1
    XP_063141284.1
    XP_063141288.1
    XP_063141298.1
    XP_063141303.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106284.1 → NP_001099754.1  leucine-rich repeat-containing protein 51

      See identical proteins and their annotated locations for NP_001099754.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473956
      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715
      Conserved Domains (2) summary
      sd00033
      Location:52 → 80
      LRR_RI; leucine-rich repeat [structural motif]
      pfam14580
      Location:89 → 173
      LRR_9; Leucine-rich repeat

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      165690617..165709837 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006229873.5 → XP_006229935.1  leucine-rich repeat-containing protein 51 isoform X1

      See identical proteins and their annotated locations for XP_006229935.1

      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715
      Conserved Domains (2) summary
      sd00033
      Location:52 → 80
      LRR_RI; leucine-rich repeat [structural motif]
      pfam14580
      Location:89 → 173
      LRR_9; Leucine-rich repeat

    2. XM_006229874.5 → XP_006229936.1  leucine-rich repeat-containing protein 51 isoform X1

      See identical proteins and their annotated locations for XP_006229936.1

      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715
      Conserved Domains (2) summary
      sd00033
      Location:52 → 80
      LRR_RI; leucine-rich repeat [structural motif]
      pfam14580
      Location:89 → 173
      LRR_9; Leucine-rich repeat

    3. XM_063285214.1 → XP_063141284.1  leucine-rich repeat-containing protein 51 isoform X1

      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715

    4. XM_063285212.1 → XP_063141282.1  leucine-rich repeat-containing protein 51 isoform X1

      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715

    5. XM_063285218.1 → XP_063141288.1  leucine-rich repeat-containing protein 51 isoform X1

      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715

    6. XM_006229872.5 → XP_006229934.1  leucine-rich repeat-containing protein 51 isoform X1

      See identical proteins and their annotated locations for XP_006229934.1

      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715
      Conserved Domains (2) summary
      sd00033
      Location:52 → 80
      LRR_RI; leucine-rich repeat [structural motif]
      pfam14580
      Location:89 → 173
      LRR_9; Leucine-rich repeat

    7. XM_063285228.1 → XP_063141298.1  leucine-rich repeat-containing protein 51 isoform X1

      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715

    8. XM_006229871.5 → XP_006229933.1  leucine-rich repeat-containing protein 51 isoform X1

      See identical proteins and their annotated locations for XP_006229933.1

      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715
      Conserved Domains (2) summary
      sd00033
      Location:52 → 80
      LRR_RI; leucine-rich repeat [structural motif]
      pfam14580
      Location:89 → 173
      LRR_9; Leucine-rich repeat

    9. XM_006229875.5 → XP_006229937.1  leucine-rich repeat-containing protein 51 isoform X1

      See identical proteins and their annotated locations for XP_006229937.1

      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715
      Conserved Domains (2) summary
      sd00033
      Location:52 → 80
      LRR_RI; leucine-rich repeat [structural motif]
      pfam14580
      Location:89 → 173
      LRR_9; Leucine-rich repeat

    10. XM_006229870.5 → XP_006229932.1  leucine-rich repeat-containing protein 51 isoform X1

      See identical proteins and their annotated locations for XP_006229932.1

      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715
      Related
      ENSRNOP00000027261.4, ENSRNOT00000027261.7
      Conserved Domains (2) summary
      sd00033
      Location:52 → 80
      LRR_RI; leucine-rich repeat [structural motif]
      pfam14580
      Location:89 → 173
      LRR_9; Leucine-rich repeat

    11. XM_063285233.1 → XP_063141303.1  leucine-rich repeat-containing protein 51 isoform X1

      UniProtKB/Swiss-Prot
      B6CZ61
      UniProtKB/TrEMBL
      A0A8I6A715
      Related
      ENSRNOP00000084027.1, ENSRNOT00000095386.2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B6CZ61.1 GenPept UniProtKB/Swiss-Prot:B6CZ61

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