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    zig-5 Zwei Ig domain protein zig-5 [ Caenorhabditis elegans ]

    Gene ID: 176527, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zig-5
    Official Full Name
    Zwei Ig domain protein zig-5
    Primary source
    WormBase:WBGene00006982
    Locus tag
    CELE_Y48A6A.1
    See related
    AllianceGenome:WB:WBGene00006982
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in pattern specification process. Predicted to be located in membrane. Is expressed in intestine and nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See zig-5 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (10951119..10953508, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Regulation of longevity by E3 ubiquitin-protein ligase Neighboring gene ncRNA Neighboring gene STE20-related kinase adapter protein strd-1 Neighboring gene BPTI/Kunitz inhibitor domain-containing protein Neighboring gene tRNA-Arg Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The secreted immunoglobulin domain proteins ZIG-5 and ZIG-8 cooperate with L1CAM/SAX-7 to maintain nervous system integrity. Bénard CY, et al. PLoS Genet, 2012. PMID 22829780, Free PMC Article
    2. Identification of spatial and temporal cues that regulate postembryonic expression of axon maintenance factors in the C. elegans ventral nerve cord. Aurelio O, et al. Development, 2003 Feb. PMID 12490565
    3. Immunoglobulin-domain proteins required for maintenance of ventral nerve cord organization. Aurelio O, et al. Science, 2002 Jan 25. PMID 11809975
    4. The small, secreted immunoglobulin protein ZIG-3 maintains axon position in Caenorhabditis elegans. Bénard C, et al. Genetics, 2009 Nov. PMID 19737747, Free PMC Article
    5. The immunoglobulin superfamily in Caenorhabditis elegans and Drosophila melanogaster. Hobert O, et al. Development, 2004 May. PMID 15128663

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in pattern specification process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Zwei Ig domain protein zig-5
    NP_499405.4
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10951119..10953508 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067004.7 → NP_499405.4  Zwei Ig domain protein zig-5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499405.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8WR47, Q9XXD7
      Conserved Domains (2) summary
      cd00096
      Location:62 → 131
      Ig; Immunoglobulin domain
      cl11960
      Location:185 → 249
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XXD7.2

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