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    ugt-9 glucuronosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 178883, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ugt-9
    Official Full Name
    glucuronosyltransferase
    Primary source
    WormBase:WBGene00020587
    Locus tag
    CELE_T19H12.1
    See related
    AllianceGenome:WB:WBGene00020587
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is expressed in pharyngeal cell. Orthologous to several human genes including UGT2A1 (UDP glucuronosyltransferase family 2 member A1 complex locus); UGT2B10 (UDP glucuronosyltransferase family 2 member B10); and UGT2B11 (UDP glucuronosyltransferase family 2 member B11). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ugt-9 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (4896048..4897969)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Acidic leucine-rich nuclear phosphoprotein 32-related protein 2 Neighboring gene glucuronosyltransferase Neighboring gene glucuronosyltransferase Neighboring gene ncRNA Neighboring gene glucuronosyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple UDP glycosyltransferases modulate benzimidazole drug sensitivity in the nematode Caenorhabditis elegans in an additive manner. Sharma N, et al. Int J Parasitol, 2024 Sep. PMID 38806068
    2. Role of UDP-Glycosyltransferase (ugt) Genes in Detoxification and Glycosylation of 1-Hydroxyphenazine (1-HP) in Caenorhabditis elegans. Asif MZ, et al. Chem Res Toxicol, 2024 Apr 15. PMID 38488606, Free PMC Article
    3. Aryl Hydrocarbon Receptor-Dependent and -Independent Pathways Mediate Curcumin Anti-Aging Effects. Brinkmann V, et al. Antioxidants (Basel), 2022 Mar 23. PMID 35453298, Free PMC Article
    4. An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans. Budovskaya YV, et al. Cell, 2008 Jul 25. PMID 18662544, Free PMC Article
    5. Effects of sod gene overexpression and deletion mutation on the expression profiles of reporter genes of major detoxification pathways in Caenorhabditis elegans. Back P, et al. Exp Gerontol, 2010 Aug. PMID 20096764

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glucuronosyltransferase
    NP_001123019.1
    • Confirmed by transcript evidence
    NP_504312.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      4896048..4897969
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071911.7 → NP_504312.1  glucuronosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504312.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01617
      Conserved Domains (2) summary
      PHA03392
      Location:20 → 462
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:30 → 532
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    2. NM_001129547.5 → NP_001123019.1  glucuronosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001123019.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZ88
      Conserved Domains (1) summary
      PHA03392
      Location:209 → 461
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
    Nucleotide Protein
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