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    col-176 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181219, updated on 9-Dec-2024

    Summary

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    Official Symbol
    col-176
    Official Full Name
    Nematode cuticle collagen N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00000749
    Locus tag
    CELE_ZC373.7
    See related
    AllianceGenome:WB:WBGene00000749
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See col-176 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    2
    Sequence:
    Chromosome: X; NC_003284.9 (10077597..10078728)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene putative methylthioribulose-1-phosphate dehydratase Neighboring gene Protein dao-4 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Further Extension of Lifespan by Unc-43/CaMKII and Egl-8/PLCβ Mutations in Germline-Deficient Caenorhabditis elegans. Mack HID, et al. Cells, 2022 Nov 8. PMID 36428956, Free PMC Article
    2. Cell-Specific mRNA Profiling of the Caenorhabditis elegans Somatic Gonadal Precursor Cells Identifies Suites of Sex-Biased and Gonad-Enriched Transcripts. Kroetz MB, et al. G3 (Bethesda), 2015 Oct 23. PMID 26497144, Free PMC Article
    3. Loss of an H3K9me anchor rescues laminopathy-linked changes in nuclear organization and muscle function in an Emery-Dreifuss muscular dystrophy model. Harr JC, et al. Genes Dev, 2020 Apr 1. PMID 32139421, Free PMC Article
    4. Ketamine induces apical extracellular matrix modifications in Caenorhabditis elegans. Yücel D. Sci Rep, 2022 Dec 21. PMID 36543791, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nematode cuticle collagen N-terminal domain-containing protein
    NP_509692.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      10077597..10078728
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077291.7 → NP_509692.1  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509692.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23263
      Conserved Domains (2) summary
      pfam01391
      Location:150 → 190
      Collagen; Collagen triple helix repeat (20 copies)
      smart01088
      Location:6 → 58
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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