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    ins-17 Insulin-like peptide 17 [ Caenorhabditis elegans ]

    Gene ID: 175585, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ins-17
    Official Full Name
    Insulin-like peptide 17
    Primary source
    WormBase:WBGene00002100
    Locus tag
    CELE_F56F3.6
    See related
    AllianceGenome:WB:WBGene00002100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in dauer larval development. Predicted to be located in extracellular region. Is expressed in several structures, including coelomocyte; egg-laying apparatus; gonad; head; and nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ins-17 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003281.10 (4476918..4477572, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein eS1 Neighboring gene Chondroitin proteoglycan 1 Neighboring gene Transcription factor atf-7 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Caenorhabditis elegans insulin-like peptide, INS-17: its physiological function and expression pattern. Matsunaga Y, et al. Biosci Biotechnol Biochem, 2012. PMID 23132577
    2. Identification and analysis of insulin like peptides in nematode secretomes provide targets for parasite control. Gahoi S, et al. Bioinformation, 2016. PMID 28356679, Free PMC Article
    3. Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson's disease. Haque R, et al. Oncotarget, 2020 Feb 11. PMID 32110282, Free PMC Article
    4. Dauer signalling pathway model for Haemonchus contortus. Ma G, et al. Parasit Vectors, 2019 Apr 29. PMID 31036054, Free PMC Article
    5. Gene expression changes associated with aging in C. elegans. Golden TR, et al. WormBook, 2007 Feb 12. PMID 18050504, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. physiological function and expression pattern of INS-17
      Title: A Caenorhabditis elegans insulin-like peptide, INS-17: its physiological function and expression pattern.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in dauer larval development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Insulin-like peptide 17
    NP_497911.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      4476918..4477572 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065510.8 → NP_497911.1  Insulin-like peptide 17 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497911.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G5EFH1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G5EFH1.1

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