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    zig-8 Zwei Ig domain protein zig-8 [ Caenorhabditis elegans ]

    Gene ID: 176732, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zig-8
    Official Full Name
    Zwei Ig domain protein zig-8
    Primary source
    WormBase:WBGene00006985
    Locus tag
    CELE_Y39E4B.8
    See related
    AllianceGenome:WB:WBGene00006985
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in synapse organization. Predicted to be located in extracellular region. Predicted to be active in neuron projection membrane. Is expressed in head; nervous system; and pharyngeal muscle cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See zig-8 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (13119820..13133938)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Palmitoyltransferase Neighboring gene ncRNA Neighboring gene Beta-1,3-galactosyltransferase bre-2;Hexosyltransferase Neighboring gene NR LBD domain-containing protein Neighboring gene ABC transporter, class E

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The secreted immunoglobulin domain proteins ZIG-5 and ZIG-8 cooperate with L1CAM/SAX-7 to maintain nervous system integrity. Bénard CY, et al. PLoS Genet, 2012. PMID 22829780, Free PMC Article
    2. Immunoglobulin-domain proteins required for maintenance of ventral nerve cord organization. Aurelio O, et al. Science, 2002 Jan 25. PMID 11809975
    3. The small, secreted immunoglobulin protein ZIG-3 maintains axon position in Caenorhabditis elegans. Bénard C, et al. Genetics, 2009 Nov. PMID 19737747, Free PMC Article
    4. The immunoglobulin superfamily in Caenorhabditis elegans and Drosophila melanogaster. Hobert O, et al. Development, 2004 May. PMID 15128663
    5. Immunoglobulin superfamily proteins in Caenorhabditis elegans. Teichmann SA, et al. J Mol Biol, 2000 Mar 10. PMID 10698639

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in neuron projection membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Zwei Ig domain protein zig-8
    NP_499714.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      13119820..13133938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067313.7 → NP_499714.1  Zwei Ig domain protein zig-8 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499714.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G5ED00
      Conserved Domains (3) summary
      cd00096
      Location:55 → 129
      Ig; Immunoglobulin domain
      smart00410
      Location:158 → 227
      IG_like; Immunoglobulin like
      pfam00047
      Location:158 → 229
      ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G5ED00.1

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