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    R102.4 Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein;Beta_elim_lyase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177961, updated on 9-Dec-2024

    Summary

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    Official Symbol
    R102.4
    Official Full Name
    Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein;Beta_elim_lyase domain-containing protein
    Primary source
    WormBase:WBGene00011291
    Locus tag
    CELE_R102.4
    See related
    AllianceGenome:WB:WBGene00011291
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable L-allo-threonine aldolase activity. Predicted to be involved in glycine biosynthetic process and threonine catabolic process. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See R102.4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    11
    Sequence:
    Chromosome: IV; NC_003282.8 (10691980..10695226, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene DUF4440 domain-containing protein Neighboring gene ncRNA Neighboring gene F-box domain-containing protein Neighboring gene TransThyretin-Related family domain Neighboring gene ncRNA Neighboring gene Allophagy receptor allo-1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables L-allo-threonine aldolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in threonine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein;Beta_elim_lyase domain-containing protein
    NP_001076701.2
    • Confirmed by transcript evidence
    NP_001255502.1
    • Confirmed by transcript evidence
    NP_001370260.1
    • Confirmed by transcript evidence
    NP_501978.3
    • Confirmed by transcript evidence
    NP_501979.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10691980..10695226 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268573.4 → NP_001255502.1  Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255502.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C6KRK8
      Conserved Domains (1) summary
      pfam01212
      Location:38 → 347
      Beta_elim_lyase; Beta-eliminating lyase

    2. NM_069577.6 → NP_501978.3  Beta_elim_lyase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501978.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21890
      Conserved Domains (1) summary
      pfam01212
      Location:63 → 352
      Beta_elim_lyase; Beta-eliminating lyase

    3. NM_001383195.1 → NP_001370260.1  Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      C6KRK9
      Conserved Domains (1) summary
      pfam01212
      Location:38 → 163
      Beta_elim_lyase; Beta-eliminating lyase

    4. NM_069578.8 → NP_501979.3  Beta_elim_lyase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501979.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0G823, Q21890, Q8T8M5, Q8T8M6
      Conserved Domains (1) summary
      pfam01212
      Location:68 → 357
      Beta_elim_lyase; Beta-eliminating lyase

    5. NM_001083232.5 → NP_001076701.2  Beta_elim_lyase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001076701.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21890
      Conserved Domains (1) summary
      pfam01212
      Location:38 → 327
      Beta_elim_lyase; Beta-eliminating lyase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q21890.3

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