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    chdp-1 Calponin homology domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172326, updated on 9-Dec-2024

    Summary

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    Official Symbol
    chdp-1
    Official Full Name
    Calponin homology domain-containing protein
    Primary source
    WormBase:WBGene00015687
    Locus tag
    CELE_C10G11.7
    See related
    AllianceGenome:WB:WBGene00015687
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in nervous system development. Predicted to be located in cell cortex; growth cone; and plasma membrane. Is expressed widely. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See chdp-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (6284973..6289340)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Verprolin-like Neighboring gene Pantothenate kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Calponin Family Member CHDP-1 Interacts with Rac/CED-10 to Promote Cell Protrusions. Guan L, et al. PLoS Genet, 2016 Jul. PMID 27415421, Free PMC Article
    2. Identification of muscle-specific regulatory modules in Caenorhabditis elegans. Zhao G, et al. Genome Res, 2007 Mar. PMID 17284674, Free PMC Article
    3. The cell cortex-localized protein CHDP-1 is required for dendritic development and transport in C. elegans neurons. Zhao T, et al. PLoS Genet, 2022 Sep. PMID 36126047, Free PMC Article
    4. Proteomic analysis of Caenorhabditis elegans. Jeong PY, et al. Methods Mol Biol, 2009. PMID 19381582
    5. Stable-isotope labeling with amino acids in nematodes. Larance M, et al. Nat Methods, 2011 Aug 28. PMID 21874007, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in growth cone IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Calponin homology domain-containing protein
    NP_491813.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6284973..6289340
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059412.7 → NP_491813.1  Calponin homology domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491813.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P91027
      Conserved Domains (1) summary
      cd00014
      Location:123 → 243
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

    RNA

    1. NR_136357.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P91027.1

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