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    algn-13 UDP-N-acetylglucosamine transferase subunit ALG13 [ Caenorhabditis elegans ]

    Gene ID: 179890, updated on 9-Dec-2024

    Summary

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    Official Symbol
    algn-13
    Official Full Name
    UDP-N-acetylglucosamine transferase subunit ALG13
    Primary source
    WormBase:WBGene00011193
    Locus tag
    CELE_R10D12.12
    See related
    AllianceGenome:WB:WBGene00011193
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 36. Orthologous to human ALG13 (ALG13 UDP-N-acetylglucosaminyltransferase subunit). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See algn-13 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (13961245..13961977, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Sugar transporter SWEET Neighboring gene Protein kinase domain-containing protein Neighboring gene Serpentine Receptor, class H Neighboring gene CCD97-like C-terminal domain-containing protein Neighboring gene GYF domain-containing protein;Suppressor of aph-1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RNAi screening of human glycogene orthologs in the nematode Caenorhabditis elegans and the construction of the C. elegans glycogene database. Akiyoshi S, et al. Glycobiology, 2015 Jan. PMID 25091817, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in dolichol-linked oligosaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UDP-N-acetylglucosamine transferase subunit ALG13
    NP_506467.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      13961245..13961977 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074066.7 → NP_506467.1  UDP-N-acetylglucosamine transferase subunit ALG13 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506467.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P92012
      Conserved Domains (1) summary
      pfam04101
      Location:3 → 173
      Glyco_tran_28_C; Glycosyltransferase family 28 C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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