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    Y53G8B.1 maleylacetoacetate isomerase [ Caenorhabditis elegans ]

    Gene ID: 190243, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y53G8B.1
    Official Full Name
    maleylacetoacetate isomerase
    Primary source
    WormBase:WBGene00021817
    Locus tag
    CELE_Y53G8B.1
    See related
    AllianceGenome:WB:WBGene00021817
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable glutathione transferase activity and maleylacetoacetate isomerase activity. Predicted to be involved in L-phenylalanine catabolic process and glutathione metabolic process. Predicted to be located in cytoplasm. Predicted to be active in mitochondrion. Orthologous to human GSTZ1 (glutathione S-transferase zeta 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y53G8B.1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (3129277..3131649)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene Magnesium transporter NIPA2 Neighboring gene Detyrosinated tubulin alpha-3 chain Neighboring gene UPF0506 domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glutathione transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables maleylacetoacetate isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables maleylacetoacetate isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-phenylalanine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in L-phenylalanine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in aromatic amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glutathione metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tyrosine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    maleylacetoacetate isomerase
    NP_497662.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      3129277..3131649
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065261.5 → NP_497662.1  maleylacetoacetate isomerase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497662.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N4S0
      Conserved Domains (3) summary
      cd03191
      Location:89 → 207
      GST_C_Zeta; C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases
      TIGR01262
      Location:18 → 211
      maiA; maleylacetoacetate isomerase
      cl00388
      Location:5 → 76
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
    Nucleotide Protein
    Heading Accession and Version

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