U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    T23G11.7 HAUS6_N domain-containing protein;Vacuolar protein sorting-associated protein VTA1 homolog [ Caenorhabditis elegans ]

    Gene ID: 172528, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    T23G11.7
    Official Full Name
    HAUS6_N domain-containing protein;Vacuolar protein sorting-associated protein VTA1 homolog
    Primary source
    WormBase:WBGene00011972
    Locus tag
    CELE_T23G11.7
    See related
    AllianceGenome:WB:WBGene00011972
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable SNARE binding activity. Predicted to be involved in SNARE complex assembly. Predicted to be located in endosome membrane. Predicted to be active in endosome and lytic vacuole. Orthologous to human UVRAG (UV radiation resistance associated). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See T23G11.7 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (7679448..7683045)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Golgin-84 Neighboring gene Rho-GAP domain-containing protein Neighboring gene eLRR (extracellular Leucine-Rich Repeat) ONly Neighboring gene Hepatocellular carcinoma-associated antigen 59

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Pairing centers recruit a Polo-like kinase to orchestrate meiotic chromosome dynamics in C. elegans. Harper NC, et al. Dev Cell, 2011 Nov 15. PMID 22018922, Free PMC Article
    2. A snapshot of the physical and functional wiring of the Eps15 homology domain network in the nematode. Tsushima H, et al. PLoS One, 2013. PMID 23424658, Free PMC Article
    3. Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Zinovyeva AY, et al. Proc Natl Acad Sci U S A, 2015 Sep 22. PMID 26351692, Free PMC Article
    4. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in SNARE complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in late endosome to vacuole transport via multivesicular body sorting pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in lytic vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    HAUS6_N domain-containing protein;Vacuolar protein sorting-associated protein VTA1 homolog
    NP_001379199.1
    • Confirmed by transcript evidence
    NP_492139.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7679448..7683045
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392592.1 → NP_001379199.1  HAUS6_N domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      P90969

    2. NM_059738.8 → NP_492139.3  Vacuolar protein sorting-associated protein VTA1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492139.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45812
      Conserved Domains (1) summary
      pfam04652
      Location:17 → 147
      Vta1; Vta1 like
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools