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    R07E4.3 Cytochrome b-c1 complex subunit 8 [ Caenorhabditis elegans ]

    Gene ID: 180862, updated on 9-Dec-2024

    Summary

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    Official Symbol
    R07E4.3
    Official Full Name
    Cytochrome b-c1 complex subunit 8
    Primary source
    WormBase:WBGene00019937
    Locus tag
    CELE_R07E4.3
    See related
    AllianceGenome:WB:WBGene00019937
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 4. Orthologous to human UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See R07E4.3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_003284.9 (5953458..5953730)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Nucleoside-diphosphatase mig-23 Neighboring gene VWFA domain-containing protein Neighboring gene ncRNA Neighboring gene Fibronectin type-III domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex III IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of respiratory chain complex III IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cytochrome b-c1 complex subunit 8
    NP_508996.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5953458..5953730
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076595.6 → NP_508996.1  Cytochrome b-c1 complex subunit 8 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508996.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21817
      Conserved Domains (1) summary
      pfam02939
      Location:11 → 87
      UcrQ; UcrQ family
    Nucleotide Protein
    Heading Accession and Version

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