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    glb-10 Globin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 183015, updated on 9-Dec-2024

    Summary

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    Official Symbol
    glb-10
    Official Full Name
    Globin domain-containing protein
    Primary source
    WormBase:WBGene00016215
    Locus tag
    CELE_C29F5.7
    See related
    AllianceGenome:WB:WBGene00016215
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Located in plasma membrane. Is expressed in several structures, including excretory cell; gonad; neurons; non-striated muscle; and somatic nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See glb-10 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (6308114..6309298, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene START domain-containing protein Neighboring gene DOMON domain-containing protein Neighboring gene ncRNA Neighboring gene Protein EFR3 homolog Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dysregulated mir-76 mediated a protective response to nanopolystyrene by modulating heme homeostasis related molecular signaling in nematode Caenorhabditis elegans. Liu H, et al. Ecotoxicol Environ Saf, 2021 Apr 1. PMID 33550076
    2. Combinational exposure to hydroxyatrazine increases neurotoxicity of polystyrene nanoparticles on Caenorhabditis elegans. Wang Y, et al. Sci Total Environ, 2023 Jul 1. PMID 37019222
    3. Nanoplastic Exposure at Predicted Environmental Concentrations Induces Activation of Germline Ephrin Signal Associated with Toxicity Formation in the Caenorhabditis elegans Offspring. Zhao Y, et al. Toxics, 2022 Nov 17. PMID 36422907, Free PMC Article
    4. Exposure to 6-PPD Quinone at Environmentally Relevant Concentrations Causes Abnormal Locomotion Behaviors and Neurodegeneration in Caenorhabditis elegans. Hua X, et al. Environ Sci Technol, 2023 Mar 28. PMID 36913653
    5. Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family. Hoogewijs D, et al. BMC Genomics, 2007 Oct 4. PMID 17916248, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxygen binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxygen carrier activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in oxygen transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    Globin domain-containing protein
    NP_495268.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      6308114..6309298 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062867.4 → NP_495268.1  Globin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495268.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18311
      Conserved Domains (1) summary
      pfam00042
      Location:32 → 140
      Globin
    Nucleotide Protein
    Heading Accession and Version

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