C37H5.5 Nucleolar complex protein 3 homolog [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C37H5.5
Official Full Name: Nucleolar complex protein 3 homolog
Primary source: WormBase:WBGene00016508
Locus tag: CELE_C37H5.5
See related: AllianceGenome:WB:WBGene00016508
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable chromatin binding activity. Predicted to be involved in DNA replication initiation. Predicted to be located in nucleus. Predicted to be active in nucleolus. Orthologous to human NOC3L (NOC3 like DNA replication regulator). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C37H5.5 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 8

Sequence:: Chromosome: V; NC_003283.11 (4827360..4836019)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C37H5.5 (e-PCR)
- UniSTS:308738

C37H5.8 (e-PCR)
- UniSTS:308740

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in DNA replication initiation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Nucleolar complex protein 3 homolog

NP_504292.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

4827360..4836019

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_071891.8 → NP_504292.2 Nucleolar complex protein 3 homolog [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_504292.2

Status: REVIEWED

UniProtKB/Swiss-Prot

P91136

Conserved Domains (3) summary

COG5117
Location:196 → 679

NOC3; Protein involved in the nuclear export of pre-ribosomes [Translation, ribosomal structure and biogenesis / Intracellular trafficking and secretion]

pfam03914
Location:542 → 700

CBF; CBF/Mak21 family

pfam07540
Location:203 → 298

NOC3p; Nucleolar complex-associated protein