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    nra-2 Nicalin [ Caenorhabditis elegans ]

    Gene ID: 172803, updated on 9-Dec-2024

    Summary

    Official Symbol
    nra-2
    Official Full Name
    Nicalin
    Primary source
    WormBase:WBGene00011488
    Locus tag
    CELE_T05F1.1
    See related
    AllianceGenome:WB:WBGene00011488
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in protein-containing complex assembly and regulation of protein targeting to membrane. Located in endoplasmic reticulum. Is expressed in body wall musculature; egg-laying apparatus; excretory canal; neurons; and pharyngeal muscle cell. Orthologous to human NCLN (nicalin). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See nra-2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (9620227..9622377)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene putative histone-binding protein rba-1 Neighboring gene putative histone-binding protein lin-53 Neighboring gene F-box associated domain-containing protein Neighboring gene Small ribosomal subunit protein eS19

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in endoplasmic reticulum PubMed 
    located_in endoplasmic reticulum  
    is_active_in endoplasmic reticulum membrane  
    located_in endoplasmic reticulum membrane  
    located_in membrane  

    General protein information

    Preferred Names
    Nicalin
    NP_001122514.1
    • Confirmed by transcript evidence
    NP_492553.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9620227..9622377
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129042.4 → NP_001122514.1  Nicalin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122514.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A5JYX8, O18033
      Conserved Domains (1) summary
      cd03882
      Location:121 → 430
      M28_nicalin_like; M28 Zn-Peptidase Nicalin, Nicastrin-like protein
    2. NM_060152.5 → NP_492553.1  Nicalin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492553.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O18033
      Conserved Domains (1) summary
      cd03882
      Location:124 → 424
      M28_nicalin_like; M28 Zn-Peptidase Nicalin, Nicastrin-like protein
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