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    D2045.9 Glycosyltransferase 25 family member [ Caenorhabditis elegans ]

    Gene ID: 3565069, updated on 9-Dec-2024

    Summary

    Official Symbol
    D2045.9
    Official Full Name
    Glycosyltransferase 25 family member
    Primary source
    WormBase:WBGene00008426
    Locus tag
    CELE_D2045.9
    See related
    AllianceGenome:WB:WBGene00008426
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable procollagen galactosyltransferase activity. Is expressed in body wall musculature; enteric muscle; and reproductive system. Human ortholog(s) of this gene implicated in brain small vessel disease 3. Orthologous to several human genes including COLGALT1 (collagen beta(1-O)galactosyltransferase 1) and COLGALT2 (collagen beta(1-O)galactosyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See D2045.9 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (10475245..10479788)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene non-specific serine/threonine protein kinase Neighboring gene Cullin-1 Neighboring gene non-specific serine/threonine protein kinase Neighboring gene BTB domain-containing protein

    General protein information

    Preferred Names
    Glycosyltransferase 25 family member
    NP_001021233.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10475245..10479788
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026062.5NP_001021233.1  Glycosyltransferase 25 family member [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021233.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18989
      Conserved Domains (1) summary
      cd06532
      Location:291473
      Glyco_transf_25; Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of ...