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    Y55F3BR.1 ATP-dependent RNA helicase DDX1 [ Caenorhabditis elegans ]

    Gene ID: 176913, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y55F3BR.1
    Official Full Name
    ATP-dependent RNA helicase DDX1
    Primary source
    WormBase:WBGene00021938
    Locus tag
    CELE_Y55F3BR.1
    See related
    AllianceGenome:WB:WBGene00021938
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and exonuclease activity. Orthologous to human DDX1 (DEAD-box helicase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y55F3BR.1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    9
    Sequence:
    Chromosome: IV; NC_003282.8 (874791..881910)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene BPTI/Kunitz inhibitor domain-containing protein;EB domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MAP kinase-activated protein kinase mak-2 Neighboring gene F-box C protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Couillault C, et al. Nat Immunol, 2004 May. PMID 15048112
    2. Functional identification of microRNA-centered complexes in C. elegans. Hebbar S, et al. Sci Rep, 2022 May 3. PMID 35504914, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ATP-dependent RNA helicase DDX1
    NP_500004.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      874791..881910
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067603.7 → NP_500004.2  ATP-dependent RNA helicase DDX1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500004.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N341
      Conserved Domains (4) summary
      COG0513
      Location:278 → 614
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
      pfam00271
      Location:492 → 599
      Helicase_C; Helicase conserved C-terminal domain
      cd12873
      Location:89 → 244
      SPRY_DDX1; SPRY domain associated with DEAD box gene DDX1
      cl21455
      Location:282 → 420
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

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