F23H11.2 TATA box-binding protein-associated factor RNA polymerase I subunit B [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: F23H11.2
Official Full Name: TATA box-binding protein-associated factor RNA polymerase I subunit B
Primary source: WormBase:WBGene00017758
Locus tag: CELE_F23H11.2
See related: AllianceGenome:WB:WBGene00017758
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly and nucleolar large rRNA transcription by RNA polymerase I. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I core factor complex and RNA polymerase transcription factor SL1 complex. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See F23H11.2 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 13

Sequence:: Chromosome: III; NC_003281.10 (895747..900158)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F23H11.2 (e-PCR)
- UniSTS:309917

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA polymerase I core promoter sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase I core promoter sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA polymerase I core promoter sequence-specific DNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA polymerase I preinitiation complex assembly	IEA Inferred from Electronic Annotation more info
involved_in RNA polymerase I preinitiation complex assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in nucleolar large rRNA transcription by RNA polymerase I	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase I	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of RNA polymerase I core factor complex	IBA Inferred from Biological aspect of Ancestor more info
part_of RNA polymerase I core factor complex	IEA Inferred from Electronic Annotation more info
part_of RNA polymerase transcription factor SL1 complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: TATA box-binding protein-associated factor RNA polymerase I subunit B

NP_497287.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

895747..900158

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_064886.6 → NP_497287.2 TATA box-binding protein-associated factor RNA polymerase I subunit B [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_497287.2

Status: REVIEWED

UniProtKB/Swiss-Prot

O01914

Conserved Domains (1) summary

pfam11781
Location:3 → 30

RRN7; RNA polymerase I-specific transcription initiation factor Rrn7