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    akir-1 Akirin [ Caenorhabditis elegans ]

    Gene ID: 171997, updated on 9-Dec-2024

    Summary

    Official Symbol
    akir-1
    Official Full Name
    Akirin
    Primary source
    WormBase:WBGene00017088
    Locus tag
    CELE_E01A2.6
    See related
    AllianceGenome:WB:WBGene00017088
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transcription coregulator activity. Involved in meiotic sister chromatid cohesion and protein import into nucleus. Located in nucleus. Is expressed in body wall musculature; hypodermis; and nervous system. Orthologous to several human genes including AKIRIN2 (akirin 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See akir-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (4137161..4138952, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Serrate RNA effector molecule homolog Neighboring gene Diphthine--ammonia ligase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GCS light chain Neighboring gene Arylesterase Neighboring gene SMP-30/Gluconolactonase/LRE-like region domain-containing protein

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in meiotic sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein import into nucleus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Akirin
    NP_491304.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4137161..4138952 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058903.9NP_491304.1  Akirin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491304.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q966L3