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    Micall1 MICAL-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362958, updated on 9-Dec-2024

    Summary

    Official Symbol
    Micall1provided by RGD
    Official Full Name
    MICAL-like 1provided by RGD
    Primary source
    RGD:1305415
    See related
    EnsemblRapid:ENSRNOG00000026212 AllianceGenome:RGD:1305415
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305415
    Summary
    Predicted to enable identical protein binding activity; phosphatidic acid binding activity; and small GTPase binding activity. Involved in cellular response to nerve growth factor stimulus; neuron projection development; and protein localization to endosome. Located in endosome membrane. Orthologous to human MICALL1 (MICAL like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 75.4), Testes (RPKM 46.5) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Micall1 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (112557192..112587618)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (110676706..110707171)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (120343900..120375151)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene transfer RNA valine (anticodon AAC) 17 Neighboring gene eukaryotic translation initiation factor 3, subunit L Neighboring gene similar to human chromosome 22 open reading frame 23 Neighboring gene RNA polymerase II, I and III subunit F Neighboring gene SRY-box transcription factor 10

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidic acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatidic acid binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to nerve growth factor stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in endocytic recycling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endocytic recycling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in neuron projection development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in neuron projection development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in plasma membrane tubulation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in plasma membrane tubulation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in plasma membrane tubulation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein localization to endosome IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein localization to endosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein localization to endosome ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein targeting to membrane IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein targeting to membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein targeting to membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in receptor-mediated endocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in receptor-mediated endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in receptor-mediated endocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in slow endocytic recycling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in slow endocytic recycling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in slow endocytic recycling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasmic side of endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic side of endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic side of endosome membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    NOT located_in early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in late endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in late endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in late endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in late endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in recycling endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    NOT located_in recycling endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in recycling endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in recycling endosome membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    NOT located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001419632.1NP_001406561.1  MICAL-like protein 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/Swiss-Prot
      D3ZQL6
      UniProtKB/TrEMBL
      A6HSP7
      Related
      ENSRNOP00000034618.4, ENSRNOT00000036357.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      112557192..112587618
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)