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    hpr-9 Cell cycle checkpoint control protein;Cell cycle checkpoint protein hpr-9 [ Caenorhabditis elegans ]

    Gene ID: 176483, updated on 9-Dec-2024

    Summary

    Official Symbol
    hpr-9
    Official Full Name
    Cell cycle checkpoint control protein;Cell cycle checkpoint protein hpr-9
    Primary source
    WormBase:WBGene00001997
    Locus tag
    CELE_Y39A1A.23
    See related
    AllianceGenome:WB:WBGene00001997
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in DNA integrity checkpoint signaling; DNA repair; and cellular response to ionizing radiation. Predicted to be located in nucleus. Predicted to be part of checkpoint clamp complex. Orthologous to several human genes including RAD9B (RAD9 checkpoint clamp component B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See hpr-9 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    12
    Sequence:
    Chromosome: III; NC_003281.10 (10621551..10626398)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Large ribosomal subunit protein uL22m Neighboring gene eLRR (extracellular Leucine-Rich Repeat) ONly Neighboring gene ncRNA Neighboring gene tRNA-Thr Neighboring gene Sugar transporter SWEET Neighboring gene Gamma-tubulin complex component Neighboring gene Uncharacterized protein Neighboring gene ncRNA

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in DNA damage checkpoint signaling  
    involved_in DNA repair  
    involved_in DNA replication checkpoint signaling  
    involved_in cellular response to ionizing radiation  
    involved_in mitotic intra-S DNA damage checkpoint signaling  
    Component Evidence Code Pubs
    part_of checkpoint clamp complex  
    part_of checkpoint clamp complex  
    located_in nucleus  

    General protein information

    Preferred Names
    Cell cycle checkpoint control protein;Cell cycle checkpoint protein hpr-9
    NP_001368495.1
    • Confirmed by transcript evidence
    NP_499342.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10621551..10626398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066941.7 → NP_499342.3  Cell cycle checkpoint protein hpr-9 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95Q27
      Conserved Domains (1) summary
      pfam04139
      Location:40 → 299
      Rad9; Rad9
    2. NM_001379907.1 → NP_001368495.1  Cell cycle checkpoint control protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1W7LFZ8
      Conserved Domains (1) summary
      pfam04139
      Location:16 → 275
      Rad9
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