cldn8.1 claudin 8.1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cldn8.1provided by ZNC
Official Full Name: claudin 8.1provided by ZNC
Primary source: ZFIN:ZDB-GENE-011018-1
See related: AllianceGenome:ZFIN:ZDB-GENE-011018-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cldn8; cldn8b; zgc:91900; wu:fa01e05
Summary: Predicted to enable structural molecule activity. Predicted to be located in bicellular tight junction and membrane. Is expressed in diencephalon; gill; integument; pleuroperitoneal region; and sensory system. Orthologous to human CLDN8 (claudin 8). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 15

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (42582685..42584552)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (42626343..42628210)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in bicellular tight junction assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in biological_process	ND No biological Data available more info
involved_in cell adhesion	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in anchoring junction	IEA Inferred from Electronic Annotation more info
is_active_in bicellular tight junction	IBA Inferred from Biological aspect of Ancestor more info
located_in bicellular tight junction	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: claudin-8

Names: claudin 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003733.1 → NP_001003733.1 claudin-8

See identical proteins and their annotated locations for NP_001003733.1

Status: PROVISIONAL

Source sequence(s)

BC077161

UniProtKB/TrEMBL

Q6AZV9

Conserved Domains (2) summary

pfam14179
Location:197 → 255

YppG; YppG-like protein

cl21598
Location:5 → 182

PMP22_Claudin; PMP-22/EMP/MP20/Claudin family